Dave Perkins is an American guitarist, and record producer.

Perkins is known for producing gritty rock and roll records for artists like Over the Rhine (Films for Radio), Steve Taylor (I Predict in 1990), and Randy Stonehill (The Wild Frontier & Can't Buy A Miracle). He is also a session musician that has played guitars (and other instruments) on albums by Carole King, Amy Grant, and others.

In 1987, Perkins released his one and only solo project, The Innocence, on What? Records. In the early 1990s, Perkins joined Taylor to form the band Chagall Guevara. The band released one album and appeared on a couple of compilations before calling it quits. Perkins sang lead vocals on one song, "If It All Comes True," which ended the album. He was also featured prominently in the track "The Wrong George," in which the listener gets to hear an unusual phone conversation, between Perkins and a lady who is looking for a different "David Perkins," recorded on Perkin's answering machine. The entire conversation is backed by an instrumental track by Chagall Guevara. In 1996, Perkins teamed up with fellow Chagall member, Lynn Nichols to form Passafist.

Throughout his career, Perkins has recorded or performed with a wide variety of entertainers and artists including Ray Charles, Carole King, Papa John Creach, Willie Nelson, John Belushi, Over the Rhine, Squeeze, Lucinda Williams, Dolly Parton, Waylon Jennings, Hunter S. Thompson, Little River Band, Phil Keaggy, Eric Champion, Joe English, Nitty Gritty Dirt Band, Ashley Cleveland, Jack Joseph Puig, Charlie Daniels, Mylon LeFevre, Dan Huff, White Heart, Phil Madeira, Nathan East, Peter Case, Tonio K., Reed Arvin, Al Kooper, Jerry McPherson, Kim Hill, Aaron Smith and many others.